The AUGUST Group is delighted to announce the AUGUST seminar series, which will commence with four seminars online in the fall of 2021. In alignment with the scope of AUGUST, the topics of the seminars are within the field of systematic reviews and meta-analyses of preclinical studies. We aim to stimulate discussion, foster and promote collaboration and support in the field.
Systematic Reviews and Meta-analyses are crucial in evidence-based medicine and critical for the advancement of science. The methodologies are well-known in the clinical setting. However, the use in preclinical animal science is infrequent. Indeed, a vivid debate on whether the infrequent number of Systematic Reviews and meta-analyses may be part of the reason why translation to the clinical setting is failing is ongoing in the scientific community.
The AUGUST Group believe that Systematic Reviews and meta-analyses on preclinical literature have several advantages, as:
We hope to see you at our seminars.
The format will be hybrid.
TNU Coffee room, Universitetsbyen 13, 8000 Aarhus C and Zoom
AUGUST is a consortium striving to facilitate the understanding of systematic reviews and meta-analysis in preclinical science, thereby improving the standards and insights in the field.
Systematic Reviews and meta-analysis are the cores of evidence-based medicine. They are a thorough analysis of earlier conducted and published experiments, synthesizing distinct knowledge into an accessible form. Although systematic reviews are well known from the clinical setting, the use of a systematic review and meta-analysis based on preclinical literature, facilitating translation to the clinical settings is infrequent. However, there is currently strong international focus on this issue, and debates on whether the infrequent number of Systematic Reviews and Meta-analyses could be part of the reason why translation to the clinical setting is often failing. The group behind the current seminar and workshop strongly believe that systematic reviews and meta-analyses on animal literature have several advantages: they can provide information to improve scientific quality; they can lead to improved implementation of the 3Rs principles, and furthermore they can increase the translational value of animal studies.
AUGUST was originally established following implementation of the Excellence in European Doctoral Training programme between Aarhus University and University of Edinburgh. Currently AUGUST actively collaborates with CAMARADES (University of Edinburgh, United Kingdom) and SYRCLE (Radboud Medical Centre, Netherlands)
06.09 : 15-16
Merel Ritskes-Hoitinga, SYRCLE, RadboudUMC, Nijmegen, The Netherlands
The benefits of preclinical systematic reviews
04.10 : 15-16
Albert Dahan, Leiden University, Leiden, The Netherlands
Backtranslation: a systematic review of animal studies on ketamine in neuropathic pain
Birgitte Kousholt, AUGUST, Dept of Clinical Medicine, Aarhus University, Aarhus, Denmark
Reporting quality and the 3Rs in preclinical animal experimental research in 2009 and 2018: A nationwide systematic investigation
29.11 : 15-16
Cilene de Oliveira, Federal University of Santa Catarina, Florianópolis, Brazil
Sysphar: systematic review and meta-analysis for pharmacologists